Clinical Implications of CNS Penetration of Antiretroviral Drugs
- 1 January 2002
- journal article
- review article
- Published by Springer Nature in CNS Drugs
- Vol. 16 (9) , 595-609
- https://doi.org/10.2165/00023210-200216090-00002
Abstract
The CNS serves as an important sanctuary site for HIV replication. The presence of HIV in this compartment may contribute to neurological complications in individuals infected with HIV. Understanding...Keywords
This publication has 83 references indexed in Scilit:
- In Vivo Effect of α 1 -Acid Glycoprotein on Pharmacokinetics of Amprenavir, a Human Immunodeficiency Virus Protease InhibitorAntimicrobial Agents and Chemotherapy, 2001
- Clinical Pharmacokinetics of Non-Nucleoside Reverse Transcriptase InhibitorsClinical Pharmacokinetics, 2001
- Cerebrospinal-fluid HIV-1 RNA and drug concentrations after treatment with lamivudine plus zidovudine or stavudineThe Lancet, 1998
- Relationship between human immunodeficiency virus—associated dementia and viral load in cerebrospinal fluid and brainAnnals of Neurology, 1997
- Study on didanosine concentrations in cerebrospinal fluidInternational Journal of Clinical Pharmacy, 1995
- Evaluation of Safety and Efficacy of 3TC (Lamivudine) in Patients with Asymptomatic or Mildly Symptomatic Human Immunodeficiency Virus Infection: A Phase I/II StudyThe Journal of Infectious Diseases, 1995
- Concise overview of the clinical pharmacokinetics of dideoxynucleoside antiretroviral agentsInternational Journal of Clinical Pharmacy, 1995
- Effect of Continuous Intravenous Infusion of Zidovudine (AZT) in Children with Symptomatic HIV InfectionNew England Journal of Medicine, 1988
- Pharmacokinetics of 2‘,3’‐Dideoxycytidine in Patients with AIDS and Related DisordersThe Journal of Clinical Pharmacology, 1988
- RESPONSE OF HUMAN-IMMUNODEFICIENCY-VIRUS-ASSOCIATED NEUROLOGICAL DISEASE TO 3'-AZIDO-3'-DEOXYTHYMIDINEThe Lancet, 1987