The bingo model IV. The statistics of survivorship in the bingo-gamma model
- 1 November 1987
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 28 (3) , 691-701
- https://doi.org/10.1002/ajmg.1320280317
Abstract
The survivorship (time to death or failure) of a bingo‐gamma (BG) model is defined as the minimum among the waiting times for completion among k independent gamma processes. The ith process is of order ni, with a mean rate for the occurrence of hits of ai, In this paper we address the case where, for all competing processes, the order and the rate at which hits occur are the same but both they and k are unknown. We denote by k the multiplicity, by n the order or the number of hits to failure, and by a the transition parameter. The joint maximum likelihood estimator (MLE) of the three paramters of this BG process is developed. An algorithm for calculating it has been devised and a computer program in BASIC has been written. The properties of the MLE: have been explored systematically, mainly by Monte Carlo simulation. The distributions, means, variances, covariances, and correlation coefficients of the three parameters are explored for samples of size 25 and samples of size 100. Also, the simple average of the observed survival times (which gives a method of moments estimator of the mean survival) is compared with the MLE of the mean survival; the two estimators seem to be unbiased and about equally efficient.Keywords
This publication has 4 references indexed in Scilit:
- The bingo model of survivorship. III. Genetic principlesAmerican Journal of Medical Genetics, 1987
- The bingo model of survivorship. II: Statistical aspects of the bingo model of multiplicity 1 with application to hereditary polyposis of the colonAmerican Journal of Medical Genetics, 1984
- The bingo model of survivorship: 1. Probabilistic aspectsAmerican Journal of Medical Genetics, 1981
- Estimation of blood platelet survival—V. A method for the analysis of population dataJournal of Chronic Diseases, 1973