A Preliminary Trial of the Programmable Implantable Medication System for Insulin Delivery
- 31 August 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (9) , 574-579
- https://doi.org/10.1056/nejm198908313210904
Abstract
We undertook a trial to determine whether an implanted insulin-delivery system, the programmable implantable medication system (PIMS), could be used to treat patients with insulin-dependent diabetes. PIMS is a pulsatile, programmable pump with a battery life expectancy of five years. The reservoir is refilled transcutaneously every two months with a surfactant-stabilized human insulin preparation containing 400 U of insulin per milliliter.This publication has 27 references indexed in Scilit:
- ONE-YEAR TRIAL OF A REMOTE-CONTROLLED IMPLANTABLE INSULIN INFUSION SYSTEM IN TYPE I DIABETIC PATIENTSThe Lancet, 1988
- Stable insulin preparation for implanted insulin pumps. Laboratory and animal trialsDiabetes, 1987
- Effect of near normoglycaemia for two years on progression of early diabetic retinopathy, nephropathy, and neuropathy: the Oslo study.BMJ, 1986
- Developing and Assessing an Implantable Insulin Infusion Pump: Interactions of University, Industry, and GovernmentInternational Journal of Technology Assessment in Health Care, 1986
- Glycerol Prevents Insulin Precipitation and Interruption of Flow in an Implantable Insulin Infusion PumpDiabetes Care, 1983
- Total Implantation of a Remotely Controlled Insulin Minipump in a Human Insulin‐Dependent DiabeticArtificial Organs, 1982
- The Use of an Implantable Insulin Pump in the Treatment of Type II DiabetesNew England Journal of Medicine, 1982
- TREATMENT OF A TYPE II DIABETIC BY A TOTALLY IMPLANTABLE INSULIN INFUSION DEVICEThe Lancet, 1981
- Nonaggregating insulin solutions for long-term glucose control in experimental and human diabetesDiabetes, 1980
- Single-factor experiments having repeated measures on the same elements.Published by American Psychological Association (APA) ,1962