Safety and Efficacy of 0.5% Podofilox Gel in the Treatment of Anogenital Warts

Abstract
EXTERNAL GENITAL and perianal warts (anogenital warts) are caused by human papillomaviruses. Human papillomaviruses are highly prevalent in sexually active men and women, although only a minority of these infections result in overt wart disease.1 Visible warts of the genital tract and anus are commonly called condylomata acuminata. It has been estimated that in 1987 approximately 1% of the population in the United States had genital warts. Because it is believed that the presence of anogenital warts facilitates the sexual transmission of the virus,2 it is important that the warts be treated.