Avirulent Clostridium perfringens Strains Obtained by Euflavine Treatment
- 1 November 1967
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 94 (5) , 1437-+
- https://doi.org/10.1128/jb.94.5.1437-1442.1967
Abstract
Clostridium perfringens was incubated in the presence of euflavine (EU); the resistant mutants which were thus isolated had highly reduced capacity to release α-toxin. This fact was confirmed by lecithinase determinations and by immunoelectrophoresis. Injected into guinea pigs and into 6- to 7-day-old chicks, these mutants were completely avirulent. A study of their properties indicated biochemical differences between wild types and mutants.This publication has 10 references indexed in Scilit:
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