Amelioration of Familial Mediterranean Fever during Hemodialysis

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Abstract
FAMILIAL Mediterranean fever is characterized by recurrent polyserositis and fever1 2 3 and is a potentially fatal illness, owing to a high incidence of renal involvement.1 2 3 4 5 The main cause of the kidney disease is amyloidosis,4 5 6 which can be associated with renal-vein thrombosis.7 Other manifestations, such as glomerulonephritis and hypersensitivity angiitis, have also been described.5 The amyloidosis is frequent in Jews of Mediterranean (Sephardic) origin, whereas in Ashkenazi Jews and Armenians, only sporadic cases have been reported.4 , 8 During the last decade, patients with familial Mediterranean fever and terminal renal failure have been treated by regular hemodialysis and transplantation.9 10 11 12 13 14 Most cases are recorded in . . .