Ketoconazole in the prevention of experimental candidal vaginitis
- 1 February 1984
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 25 (2) , 281-282
- https://doi.org/10.1128/aac.25.2.281
Abstract
The prophylactic and therapeutic activities of ketoconazole were evaluated in rats inoculated intravaginally with Candida albicans. Daily doses of 2.5 mg/kg initiated 48 h before challenge and continued for 48 h thereafter protected 80% of the rats against infection. A similar result in rats with established infection was attained with daily doses of 5.0 mg/kg.Keywords
This publication has 2 references indexed in Scilit:
- The mechanism of action of the new antimycotic ketoconazoleThe American Journal of Medicine, 1983
- Treatment of vaginal candidiasis with ketoconazole, a new, orally active, antimycoticEuropean Journal of Obstetrics & Gynecology and Reproductive Biology, 1979