The effect of active and passive immunization against oxytocin on ovarian cyclicity in ewes
- 1 July 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 103 (3) , 337-344
- https://doi.org/10.1530/acta.0.1030337
Abstract
Active and passive immunization of ewes against oxytocin prolonged the the luteal phase of the estrous cycle, as evaluated by estrous behavior and determination of progesterone. Between the animals there was a high variability in response. In general animals with prolonged cycles had lower concentrations of free oxytocin. But in some animals oxytocin antibodies had no effect on cyclicity. An individual minimal threshold concentration for oxytocin was presumed. In control or treated animals circulating oxytocin concentrations increased parallel with progesterone concentrations but decreased earlier during the mid luteal phase of the cycle. A new increase in oxytocin concentrations was only observed if a new corpus luteum was formed.This publication has 1 reference indexed in Scilit: