Possible Role of Leukotrienes in Gastritis Associated with Campylobacter pylori

Publisher Website
Google Scholar
Abstract
This study was done to evaluate the role of leukotrienes LTs) in gastritis associated with Campylobacter pylori. Biopsy specimens of gastric mucosa were obtained endocopically from 18 patients with nonulcer dyspepsia for acteriological and histological examination and extraction f LTs. There was correlation between the LTB4 level in the nucosa and the degree of gastritis evaluated histologically. The level was higher when infiltration of neutrophils in the astric mucosa was more extensive. The LTB4 level in muosa infected with C. pylori was higher than that in noninected mucosa. These findings suggest that endogenous LTs ay be related to the pathogenesis of gastritis associated ith C. pylori.

This publication has 0 references indexed in Scilit: