Absence of correlation between DNA repair in ultraviolet irradiated mammalian cells and life span of the donor species.
- 1 January 1980
- journal article
- research article
- Published by Genetics Society of Japan in The Japanese Journal of Genetics
- Vol. 55 (2) , 99-108
- https://doi.org/10.1266/jjg.55.99
Abstract
The amounts of unscheduled DNA synthesis in fibroblasts originating from 34 spp. in 11 orders of mammals, after 10 Jm-2 UV irradiation, were assayed by autoradiography. Genome size of the species was determined by cytophotometric measurements of DNA contents of the cultured cells and the ability of unscheduled DNA synthesis per unit amount of DNA was computed. There was no correlation between repair potentials and life span, denying the presence of the correlation suggested by Hart and Setlow (1974) on 7 spp.Keywords
This publication has 3 references indexed in Scilit:
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- Relation of Lifespan to Brain Weight and Body Weight in MammalsPublished by Wiley ,1959
- Tissue nucleic acidsBiochemical Journal, 1944