INTRA-ARTERIAL RADIONUCLIDE INFUSION - NEW TECHNIQUE TO ASSESS CHEMOTHERAPY PERFUSION PATTERNS

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 62  (5) , 699-703
Abstract
A mechanical infusion pump was used to introduce 99mTc-sulfur colloid at a rate of 1 ml/min into the hepatic arteries of 6 patients with liver cancer. The radiotracer distribution patterns were compared to those obtained with bolus radionuclide angiography and those seen with standard contrast angiography. In all cases, the slow flow rate radionuclide studies evidenced dramatic differences from the patterns obtained with rapid flow rate injections. The results indicate that standard, rapid-injection contrast techniques may not produce the most reliable information regarding potential flow distribution. Radiotracers introduced at flow rates approximating those attained with infusion pumps will offer the best estimates of initial catheter placement and subsequent patterns of hepatic distribution of chemotherapeutic agents.

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