Kinetics of D-α-tocopherol in a water soluble base in man

Abstract
The kinetics of D-α-tocopherol (vitamin E) were investigated in 10 healthy, adult volunteers following a single dose of 500 iu D-α-tocopherol. Plasma concentration/time curves fitted using a one compartment open model, showed a rise to 12 ± 1.9 μmol litre−1 above endogenous values over 8-9 h and then a tailing away to 7 ± 1.1 μmol litre−1 after 24 h.

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