Intramuscular injection of procaine penicillin combined with oral administration of chloramphenicol in the treatment of gonorrhoea.

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Abstract
Five hundred male patient with gonorrhea were treated with a single intramuscular injection of 600,000 units procaine penicillin and an oral dose of 0.5 or 0.75 g of chloramphenicol swallowed under supervision. The failure rate was 5.1% in the 256 patients who were infected with gonococci less sensitive to penicillin (minimum inhibitory concentration 0.125-2 units/ml). The failure rate was less then 1% in the 244 patients infected with gonococci sensitive to penicillin (minimum inhibitory concentration 0.06 units/ml or less).