12,13-Epoxy-Δ 9 -Trichothecenes as the Probable Mycotoxins Responsible for Stachybotryotoxicosis
- 24 August 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 181 (4101) , 758-760
- https://doi.org/10.1126/science.181.4101.758
Abstract
Stachybotrys atra cultures grown on oats produced five compounds toxic to brine shrimp; three are the sesquiterpenoid mycotoxins known as 12,13-epoxy-Δ9-trichothecenes. One trichothecene is roridin E, a known metabolite of Myrothecium verrucaria. The other two were hydrolyzed to verrucarol, the product of roridin and verrucarin hydrolysis. Spectroscopic data indicate that the two remaining compounds are also 12,13-epoxy-Δ9-trichothecenes. These metabolites are probably among those responsible for stachybotryotoxicosis.Keywords
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