The ABCʼs of limb-girdle muscular dystrophy: α-sarcoglycanopathy, Bethlem myopathy, calpainopathy and more
- 1 October 2001
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Neurology
- Vol. 14 (5) , 567-573
- https://doi.org/10.1097/00019052-200110000-00004
Abstract
Limb-girdle muscular dystrophy is a class of disorders encompassing many forms of this disease. Variation exists between the inheritance patterns, genes responsible, course of disease and symptoms, with the cohesive factor among these disorders being the predominance of proximal muscle weakness. Here we review each form of limb-girdle muscular dystrophy with attention to molecular genetics, clinical features, inheritance, and diagnostic issues pertaining to each primary genetic cause.Keywords
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