The Metabolism of Glycine in Mice Treated Acutely and Chronically with Morphine

Publisher Website
Google Scholar
Abstract
In acutely and chronically treated mice morphine significantly decreased glycine in brain. The effect of nalorphine was the opposite while the application of glycine cause this aminoacid to increase in brain tissue. We suppose that the symptoms of sedation and the psychic changes caused by morphine could be partly due to the fall of glycine both after acute and chronicaapplication. The symptoms of abstinence are possibly partly caused by the increase of glycine.

This publication has 0 references indexed in Scilit: