Unusual Chromosome Abnormalities in Primary Central Nervous System Lymphoma
- 1 January 1996
- journal article
- case report
- Published by Taylor & Francis in Leukemia & Lymphoma
- Vol. 21 (5-6) , 515-517
- https://doi.org/10.3109/10428199609093453
Abstract
Primary central nervous system (PCNS) lymphoma is a relatively rare disease. The Epstein-Barr virus (EBV) has often been implicated in the development of lymphomas. Few cytogenetic studies on PCNS lymphomas have been reported. We describe here an unusual case of PCNS B cell lymphoma, centroblastic polymorphic type without coexistent immune deficiency. The cytogenetic study showed unusual abnormalities: t(1;9) (q25;p21); del (6) (q14q25), trisomy 12 and in addition one clone with trisomy 7 and loss of chromosome X. We did not observe any chromosome 14 abnormality, which is more commonly reported in PCNS lymphomas.Keywords
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