In spite of significant advances of the past two decades in the differentiation of bullous disorders, particularly from the standpoint of histopathology, certain blistering eruptions of the skin still defy accurate classification. This is true of the cases presented herein, which seem to represent an entity, puzzling to us and equally so to dermatologic colleagues elsewhere who have been privileged to observe it. Seven patients, all men but one, all middle-aged or older, have been observed over a period of several years with a persistent eruption of identical pattern which consists of grouped, pruritic vesicles confined to one or more circumscribed plaques about the head or neck, extending through a succession of annoying flares and leading eventually to scarring of the affected sites. In two instances, brief episodes of vesicular exanthems have occurred. In one case, lesions of the mouth and pharynx appeared and,