A SIMPLIFIED TEST FOR DETECTION OF PARA-AMINOSSALICYLIC ACID AND ACETYLSALICYLIC ACID METABOLITES IN URINE

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Abstract
A simplified dip-and-read iron-containing reagent strip is useful in detecting PAS or its metabolites in urine. The test is carried out by merely dipping the test strip in urine and comparing it with a color chart. Thes test has advantages over other tests since it is not influenced by variations in urinary pH or urinary phosphate. Serial studies of urine following PAS ingestion show that in the first two hours following ingestion much of the metabolite in the urine is free PAS, whereas by six hours most of the metabolite is conjugated at the amino or the carboxyl group. The test is also quite useful for the detection of salicylate in urine.

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