Accuracy of Preoperative Pinhole Subtraction Single Photon Emission Computed Tomography for Patients with Primary and Recurrent Hyperparathyroidism in an Endemic Goiter Area
- 1 June 2004
- journal article
- clinical trial
- Published by Springer Nature in Surgery Today
- Vol. 34 (6) , 493-497
- https://doi.org/10.1007/s00595-004-2746-0
Abstract
The study population consisted of 15 patients with primary (n = 13) or recurrent (n = 2) HPTH who underwent preoperative 99mTcO4-201T1 pinhole subtraction SPECT. Preoperative sonography was also done in 14 of these patients. 99mTcO4-201T1 pinhole subtraction SPECT was significantly more accurate than sonography. It had an overall accuracy of 80% in detection of enlarged parathyroid glands. The accuracy of localization increased to 92.3% in patients with solitary adenomas, and to 100% in those with solitary adenomas and no previous parathyroid exploration. The high accuracy of preoperative localization with 99mTcO4-201T1 pinhole subtraction SPECT in patients with primary and recurrent HPTH allows for an imaging-guided unilateral operative strategy in most patients, even those with concomitant nodular goiters. This may reduce the risk of surgical complications and expand the use of minimally invasive techniques in parathyroid surgery.Keywords
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