THE ANTAGONISM OF TETRACYCLINE AND FERRIC IRON IN VIVO
- 1 August 1985
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 20 (1) , 17-26
- https://doi.org/10.1099/00222615-20-1-17
Abstract
To test the hypothesis that the in-vivo antibiotic action of tetracycline might be affected by ferric iron and the enhancement of infection by ferric iron by tetracycline, the actions of intraperitoneal antibiotic and local ferric ammonium citrate, given separately and together, were measured in the dorsal skin of guinea-pigs bearing lesions due to staphylococci, streptococci, a Proteus sp., an Erysipelothrix sp., Clostridium perfringens, Pseudomonas aeruginosa, Aeromonas hydrophila and Klebsiella pneumoniae.This publication has 4 references indexed in Scilit:
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- ACTION OF IRON ON LOCAL KLEBSIELLA INFECTION OF SKIN OF GUINEA-PIG AND ITS RELATION TO DECISIVE PERIOD IN PRIMARY INFECTIVE LESIONS1976
- PRODUCTION OF SUBCUTANEOUS STAPHYLOCOCCAL SKIN LESIONS IN MICE1965
- THE VALUE AND DURATION OF DEFENCE REACTIONS OF THE SKIN TO THE PRIMARY LODGEMENT OF BACTERIA1957