Testing of saliva and serum for HIV in high-risk populations
- 1 August 1995
- journal article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 14 (8) , 710-713
- https://doi.org/10.1007/bf01690881
Abstract
Paired samples of saliva and serum from 286 highrisk subjects were tested for HIV using two commercial enzyme immunoassays following the same WHO testing strategy supplemented with a Western blot technique. Agreement between HIV testing in both sample types was 98.9 % (95 % confidence interval: 97.7–100). The sensitivity of an EIA (Wellcozyme GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7% (151/153). These results support previous data showing that in some situations saliva might be an effective alternative to serum for HIV testing.Keywords
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