Evidence of Subtle Gray-Matter Pathologic Changes in Healthy Elderly Individuals With Nonspecific White-Matter Hyperintensities
Open Access
- 1 August 2003
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 60 (8) , 1109-1112
- https://doi.org/10.1001/archneur.60.8.1109
Abstract
NONSPECIFIC white-matter hyperintensities (WMHs) are frequently seen on conventional magnetic resonance (MR) images of the brain from elderly individuals.1-3 Although the nature and clinical significance of WMHs in the elderly are still unclear, the most plausible pathological substrate for such changes is thought to be ischemic damage.4,5Keywords
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