Abstract
Thyroid I131 uptake by restrained rats was higher at one hour, and lower at 4 hours, than that of nonrestrained control animals. The lower the body temperature of the restrained animals at 4 hours, the lower the I131 uptake by the thyroid. Restrained hypothermic rats had a significantly greater thyroid uptake of I131 than equally hypothermic nonrestrained animals. It is concluded that hypothermia of restrained animals cannot be ascribed to depressed basal metabolism.

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