New Methods for the Preparation 2-Formyl-1,2,3,4-tetrahydroisoquinolinesvia N-Formyliminium Ions
- 1 January 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1987 (11) , 1031-1032
- https://doi.org/10.1055/s-1987-28162
Abstract
N-Formyl-2-phenylethylamines react with different aldehydes in acidic medium giving good yields of 2-formyl-1,2,3,4-tetrahydroisoquinolines. In situ prepared N-formyl-2-phenylethylamine (from phenethylamines in formic acid as the reaction medium) can also be used for the synthesis of the title compounds.Keywords
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