Lymphocyte counting by cell size distribution analysis of leucocytes compared with conventional blood film differential count
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 44 (3) , 211-215
- https://doi.org/10.3109/00365518409083799
Abstract
The fourteen parameter Coulter Counter S-Plus IV automated haematology analyser includes the innovative capability of calculating the percentage and number of lymphocytes in the leucocyte population. These features have been evaluated. The percentage of lymphocytes (LYP) correlates well to that of the conventional blood film differential count (CDC) and the reproducibility and linearity is excellent. The reproducibility exceeds that of the CDC and it is proposed that with a few safeguards the accuracy also is superior. The reason for possible erroneous LYPs are discussed and the safeguards to detect them are described. It is suggested that in cases where information on the percentage of lymphocytes (or granulocytes) is sufficient the CC LYP may replace the CDC. Use of LYP may reduce the number of CDCs to be performed by 50-75%.Keywords
This publication has 2 references indexed in Scilit:
- Normal values and least significant differences for differential leukocyte countsJournal of Chronic Diseases, 1975
- Differential white cell counts by frequency distribution analysis of cell volumesJournal of Clinical Pathology, 1974