Nonenzymic Joining of Oligoadenylates on a Polyuridylic Acid Template
- 2 April 1976
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4234) , 53-54
- https://doi.org/10.1126/science.1257755
Abstract
3',5'-Linked hexa-adenylic acid with a 2',3'-cyclic phosphate terminus [(A5A less than p] couples on a polyuridylic acid template in the presence of ethylenediamine to form the dodecamer (24 percent) and octadecamer (5 percent). The bond produced is largely that of the 2',5' isomer.Keywords
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