Pattern-Reversal Electroretinograms in Unilateral Glaucoma

Publisher Website
Google Scholar
Abstract
Pattern-reversal and flash electroretinograms (ERG), and oscillatory potentials (OP) were recorded from 11 patients with unilateral glaucoma. The pattern-reversal ERG amplitudes were reduced below the level of normal variation in 10 of the 11 glaucomatous eyes. The difference in amplitude means was statistically significant. No differences were observed in flash ERGs or OPs. The histopathological correlate to the visual field defects in glaucoma is retinal ganglion cell degeneration. The present electrophysiological findings support the view, based on results from animal experiments, that the pattern-reversal ERG reflects ganglion cell activity. Keywords Ganglion Cell Visual Field Defect Oscillatory Potential Glaucomatous Damage Optic Nerve Damage These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.