Physical dependence following zopiclone usage: A case report
- 1 March 1992
- journal article
- case report
- Published by Wiley in Human Psychopharmacology: Clinical and Experimental
- Vol. 7 (2) , 143-145
- https://doi.org/10.1002/hup.470070211
Abstract
A single case report is presented in which zopiclone was used in a patient as a hypnotic. The patient developed physical dependence. It is suggested that the adverse effects of zopiclone relate to its mechanism of action. Like other hypnotics it binds to the gamma‐aminobutyric acid (GABA)‐benzodiazepine‐chloride ionophore receptor complex. This may explain the means by which zopiclone can cause dependence.Keywords
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