Oceanapiside, an Antifungal Bis-α,ω-amino Alcohol Glycoside from the Marine Sponge Oceanapia phillipensis
- 23 October 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (12) , 1678-1681
- https://doi.org/10.1021/np990190v
Abstract
The structure of oceanapiside, an antifungal α,ω-bis-aminohydroxylipid glycoside from the temperate marine sponge Oceanapia sp., was elucidated by a combination of 2D NMR, chemical degradation/correlation, and MALDI MS−MS spectrometry. Oceanapiside exhibits antifungal activity against Candida glabrata at 10 μg/mL (MIC).Keywords
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