IMMOTILE CILIA SYNDROME: RADIAL SPOKES DEFICIENCY IN A PATIENT WITH KARTAGENER'S TRIAD
- 1 July 1981
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 70 (4) , 571-573
- https://doi.org/10.1111/j.1651-2227.1981.tb05742.x
Abstract
Mucociliary transport and ultrastructure of nasal cilia in a 13-yr-old boy with Kartagener''s triad were investigated. Mucociliary transport was significantly delayed (> 30 min). EM showed cilia lacking radial spokes, eccentric central tubules and a dislocation of 2 of the outer doublets. Dynein arms were present. The radial spoke defect is apparently a distinct congenital anomaly which contributes to the pathogenesis of the immotile cilia syndrome.Keywords
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