Adipokines and the insulin resistance syndrome in familial partial lipodystrophy caused by a mutation in lamin A/C
- 17 November 2005
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 48 (12) , 2641-2649
- https://doi.org/10.1007/s00125-005-0038-x
Abstract
Familial partial lipodystrophy (FPLD) and obesity are both associated with increased risks of type 2 diabetes and cardiovascular disease. Although adipokines have been implicated, few data exist in subjects with FPLD; therefore we investigated a family with FPLD due to a lamin A/C mutation in order to determine how abnormalities of the plasma adipokine profile relate to insulin resistance and the metabolic syndrome.Keywords
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