Clinical Evaluation of the Middlebrook-Dubos Hemagglutination Test

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Abstract
The Middlebrook-Dubos hemagglutination test was performed on the serum of 547 persons. The value of the test as a diagnostic procedure lies in ruling out tuberculosis. With the occasional exception of a patient who is severely ill with the disease, a serum titer of 1:8 or less probably excludes active tuberculosis. A positive reaction in a serum dilution of 1:8 or higher is only suggestive of active disease. Although 79.5% of the tuberculous patients tested were positive at 1:8 or above, 27.8% of the non-tuberculous and arrested case groups also were positive at 1:8 or above.