Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1 and Impairs Its Ability to Activate Phosphatidylinositol 3-Kinase in Response to Insulin
Open Access
- 1 February 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (5) , 3543-3549
- https://doi.org/10.1074/jbc.m007231200
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Protein Kinase C-ζ and Phosphoinositide-dependent Protein Kinase-1 Are Required for Insulin-induced Activation of ERK in Rat AdipocytesPublished by Elsevier ,1999
- In Vivo Adenoviral Delivery of Recombinant Human Protein Kinase C-ζ Stimulates Glucose Transport Activity in Rat Skeletal MusclePublished by Elsevier ,1999
- Primary Structure, Tissue Distribution, and Expression of Mouse Phosphoinositide-dependent Protein Kinase-1, a Protein Kinase That Phosphorylates and Activates Protein Kinase CζJournal of Biological Chemistry, 1999
- Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.Journal of Clinical Investigation, 1997
- Protein Kinase C-ζ as a Downstream Effector of Phosphatidylinositol 3-Kinase during Insulin Stimulation in Rat AdipocytesPublished by Elsevier ,1997
- Phosphorylation of Sendai Virus Phosphoprotein by Cellular Protein Kinase C ζPublished by Elsevier ,1997
- Activation of Protein Kinase C (α, β, and ζ) by Insulin in 3T3/L1 CellsJournal of Biological Chemistry, 1997
- Tumor Necrosis Factor α-induced Phosphorylation of Insulin Receptor Substrate-1 (IRS-1)Journal of Biological Chemistry, 1995
- Regulation of Phosphatidylinositol 3′-Kinase by Tyrosyl PhosphoproteinsPublished by Elsevier ,1995
- Potent Activation of Phosphatidylinositol 3'-Kinase by Simple Phosphotyrosine Peptides Derived from Insulin Receptor Substrate 1 Containing Two YMXM Motifs for binding SH2 DomainsBiochemistry, 1994