Controlled release levodopa treatment of motor fluctuations in Parkinson's disease.
Open Access
- 31 January 1987
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 50 (2) , 194-198
- https://doi.org/10.1136/jnnp.50.2.194
Abstract
A controlled release preparation of levodopa-carbidopa, CR III, given every 4 hours to 17 Parkinsonian patients for up to 10 months reduced plasma drug variations and improved motor response fluctuations compared with standard levodopa-carbidopa given every 2 hours. The results support the value of pharmaceutical approaches to the stabilisation of circulating levodopa levels in the treatment of Parkinson's disease.This publication has 19 references indexed in Scilit:
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