Identification and quantitation of cholanoic acids in hepatic and extra‐hepatic tissues of rat
- 1 June 1975
- Vol. 10 (6) , 340-347
- https://doi.org/10.1007/bf02532456
Abstract
Tissues of rats were examined for the presence of cholanoic acids. Quantitation of extraction, deconjugation, and isolation were verified by use of radioactive standards. Identification was made by thin layer and gas liquid chromatographic comparison to standards and mass spectrometry. All tissues examined were found to contain several conjugated cholanoic acids. Liver contained primarily cholic acid and peripheral tissues primarily dihydroxy compounds, mainly hyodeoxycholic acid.Keywords
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