Accelerator Mass Spectrometry as a Bioanalytical Tool for Nutritional Research
- 1 January 1998
- book chapter
- Published by Springer Nature
- Vol. 445, 397-410
- https://doi.org/10.1007/978-1-4899-1959-5_25
Abstract
Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but is also available for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram-sized samples. Its advantages over non-isotopic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.Keywords
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