Effect of Calcium Status, Mass of Calcium Administered and Age on Ca45 Metabolism in the Rat

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Abstract
Placing normal rats on a low Ca diet for as little as 2 days greatly increased their ability to absorb Ca45 from the tract. The specific activity of labeled Ca at the site of absorption had little effect upon its absorption. In general, younger rats absorbed more Ca45 than older ones, but there was no significant difference between 6.5 and 16-month-old animals. Interpretations involving Ca45 must include consideration of exchange reactions, and care must be given to initial selection of diets and animals, prepn. of animals for the experiment, and dietary management during the exptl. period.