Cadmium‐mediated oxidative stress in kidney proximal tubule cells induces degradation of Na + /K + ‐ATPase through proteasomal and endo‐/lysosomal proteolytic pathways
- 1 October 1999
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 13 (13) , 1751-1761
- https://doi.org/10.1096/fasebj.13.13.1751
Abstract
The mechanisms of cadmium (Cd) -dependent nephrotoxicity were studied in a rat proximal tubule (PT) cell line. CdCl2 (5 μM) increased the production of reactive oxygen species (ROS), as determined ...Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (Th 345/6‐1)
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