Formaldehyde adducts of glutathione. Structure elucidation by two-dimensional n.m.r. spectroscopy and fast-atom-bombardment tandem mass spectrometry
- 15 January 1988
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 249 (2) , 573-579
- https://doi.org/10.1042/bj2490573
Abstract
Aqueous mixtures of formaldehyde and glutathione react to form a variety of cyclized adducts in addition to S-hydroxymethylglutathione. The adducts are in labile equilibrium with each other and are not readily separated. The structures of two of the other major adducts were determined by concerted application of 13C-1H two-dimensional chemical-shift correlation, fast-atom-bombardment mass spectrometry and tandem mass spectrometry to the adduct mixtures in aqueous solution.This publication has 9 references indexed in Scilit:
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