Tissue plasminogen activator inhibitor in the epidermis
- 1 November 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 113 (5) , 523-527
- https://doi.org/10.1111/j.1365-2133.1985.tb02375.x
Abstract
The presence of a tissue plasminogen activator inhibitor in the epidermis was investigated. A partially purified tissue plasminogen activator from a Bowes melanoma cell line medium was used as a tissue plasminogen activator. Extracts of epidermis dissolved in a 10 mM phosphate buffer, pH 7.0, were found to contain a tissue plasminogen activator inhibitor. The same extracts also contained a urokinase inhibitor. It is not clear whether these inhibitors are the same. This study is the first to show the existence of a tissue plasminogen activator inhibitor in the epidermis.This publication has 21 references indexed in Scilit:
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