XI. Yeast sequencing reports. The complete sequence of an 18,002 bp segment of Saccharomyces cerevisiae chromosome XI contains the HBS1, MRP‐L20 and PRP16 genes, and six new open reading frames
- 1 February 1994
- Vol. 10 (2) , 231-245
- https://doi.org/10.1002/yea.320100210
Abstract
We report the sequence of an 18,002 bp DNA fragment from the right arm of Saccharomyces cerevisiae chromosome XI. This segment contains nine complete open reading frames (ORFs), YKR401 to YKR409, and part of another ORF, YKR400, covering altogether 87·2% of the entire sequence. One of them, YKR400, encodes an NAD‐dependent 5,10‐methylene‐tetrahydrofolate dehydrogenase. YKR404, YKR405 and YKR406 correspond to the previously characterized HBS1, MRP‐L20 and PRP16 genes, coding for a translation elongation factor, a mitochondrial ribosomal protein and an ATP‐binding protein, respectively. The putative product of YKR407 contains the zinc‐binding region signature of neutral zinc metallopeptidases. The five other ORFs do not show significant homology to any known protein. The sequence data reported here have been assigned EMBL accession number Z27116.Keywords
This publication has 26 references indexed in Scilit:
- The translation machinery and 70 kd heat shock protein cooperate in protein synthesisCell, 1992
- The complete DNA sequence of yeast chromosome IIINature, 1992
- STRUCTURE AND FUNCTION OF SIGNAL-TRANSDUCING GTP-BINDING PROTEINSAnnual Review of Biochemistry, 1991
- Eukaryotic protein elongation factorsTrends in Biochemical Sciences, 1990
- A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicingCell, 1990
- Localization of possible functional domains in sup2 gene product of the yeast Saccharomyces cerevisiaeFEBS Letters, 1987
- Sequence and structural features associated with translational initiator regions in yeast — a reviewGene, 1987
- The detection and classification of membrane-spanning proteinsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1985
- Analysis of membrane and surface protein sequences with the hydrophobic moment plotJournal of Molecular Biology, 1984
- A simple method for displaying the hydropathic character of a proteinJournal of Molecular Biology, 1982