A comparative molecular field analysis of cytochrome P450 2A5 and 2A6 inhibitors
- 1 January 2001
- journal article
- research article
- Published by Springer Nature in Journal of Computer-Aided Molecular Design
- Vol. 15 (3) , 195-202
- https://doi.org/10.1023/a:1008102217770
Abstract
Structure-activity relationships of 23 P450 2A5 and 2A6 inhibitors were analysed using the CoMFA [1] and GOLPE/GRID with smart region definition (SRD) [2]. The predictive power of the resulting...Keywords
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