RATES OF SYNTHESIS OF POLYADENYLATED MESSENGER-RNA AND RIBOSOMAL-RNA DURING CELL-CYCLE OF SCHIZOSACCHAROMYCES-POMBE - WITH AN APPENDIX - CALCULATION OF PATTERN OF PROTEIN ACCUMULATION FROM OBSERVED CHANGES IN RATE OF MESSENGER-RNA SYNTHESIS
- 1 January 1976
- journal article
- research article
- Vol. 21 (3) , 497-521
Abstract
In synchronously-dividing cultures of fission yeast (S. pombe), the rates of synthesis of polyadenylated mRNA and rRNA double after DNA synthesis. Control of the rates of synthesis of these RNAs by gene number was confirmed by inhibiting DNA synthesis with hydroxyurea. A pattern of protein accumulation during synchronous culture was calculated from changes in the rate of mRNA synthesis. This pattern was very similar to previously reported changes in enzyme activity during culture. The control of the balanced duplication of cellular components during the cell cycle by gene-number-controlled mRNA synthesis is discussed.This publication has 7 references indexed in Scilit:
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