Prognostic Value of Post-Transplant Hippurate Scintigraphy

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Abstract
131I hippurate sequential scintigrams obtained after transplantation contain prognostic information about the long-term development of a graft. Results of 131I hippurate sequential scintigrams made within 48 h after graft implantation were compared to the graft status 2 yr after transplantation. Hippurate uptake and transport were rated on a 4-step scale. Disturbed hippurate uptake and abnormal tracer transit were associated with increased frequency of early graft destruction and with a high frequency of chronic rejection. The chi-square test demonstrated a significant relationship between results of the initial hippurate scintigrams and long-term graft development.