1. The submandibular and parotid salivary gland uptake of [99mTc]pertechnetate has been measured at 3 min, 8 min and 13 min after administration in twenty-five normal subjects, seventeen patients with rheumatoid arthritis (RA) alone, seven patients with RA and keratoconjunctivitis sicca (KCS) and twenty-four patients with Sjögren's syndrome and salivary gland involvement. 2. Normal ranges for salivary gland 99mTc uptake have been established. 3. At 8 min fifteen patients with Sjögren's syndrome had a low uptake value (parotid 99mTc uptake but parotid gland involvement was more marked than submandibular. Involvement was usually bilateral. 5. In the patients with RA alone and RA and KCS a small number of patients had low uptake values.