Abstract
With the aid of an agar gel electrophoretic technique, it was revealed that the activities of esterase and alkaline phosphatase in the domesticated silkworm, Bombyx mori L., were often twice as those of the wild silkworm. It was suggested that the differentiation of Bombyx mori from Theophila mandarina might be due to a duplication of primitive genes in the silkworm by unequal crossing over rather than a mutation.

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