Incorporation of Dietary 1–O-Alkyldiacyl Glycerols into Tissue Lipids of Neonatal Rats

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Abstract
3H-[9,10]-l-O-alkyl-2,3-diacyl glycerols were administered per os to suckling rats at 1, 3, 6, 9 and 18 days of age. 12 h after administration the animals were killed and the distribution of the labelled material was analysed by whole-body autoradiography. The brown adipose tissue (BAT), intestine and liver showed the highest levels of label at all ages. The lipid content of BAT, intestine and liver were separated into lipid classes, which were analysed for their 3H levels. About 30% of the recovered label was found in the phospholipid fraction at all ages. Little of the administered dose was recovered as alkyl glycerols: 5% in the 1-day-old rat decreasing to < 1.5% at 18 days of age, indicating that dietary alkyl glycerols only to a very limited degree are incorporated in tissue ether lipids in the young rat.