B AND T LYMPHOCYTES IN MAN .2. CIRCULATING B AND T LYMPHOCYTES IN CANCER-PATIENTS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 7  (3-4) , 297-305
Abstract
B [bone marrow derived], T [thymus derived] and null lymphocytes from 87 coded peripheral blood samples from 33 normals and 54 nonoperable or progressive cancer patients were determined. The controls have higher mean numbers of circulating lymphocytes than the cancer patients. Radiation-treated cancer patients have lower values than nonirradiated patients. This phenomenon is also seen in the relative and absolute T, but not the B lymphocytes. There was no difference in the relative frequencies of the B lymphocytes among the different groups of patients. However, the controls have the highest and the radiation-treated cancer patients have the lowest absolute numbers of B lymphocytes. Although cancer patients have higher relative numbers of null cells than the controls, only the difference between the controls and the radiation-treated cancer patients was statistically significant.

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