A micrometabolic inhibition test for the estimation of poliovirus neutralizing antibodies.

  • 1 January 1972
    • journal article
    • Vol. 47  (2) , 171-5
Abstract
A modified micrometabolic inhibition test for the titration of poliovirus neutralizing antibodies is described. The effects of varying both the duration and the temperature of incubation of the serum-virus mixtures were examined. Overnight incubation resulted in a 2-3-fold increase in the titre of the hyperimmune sera tested. The method is simple and economical and appears to be suitable for antibody surveys.